Data Description file for Dataset: Functional Annotation - InterPro Description: Dataset of target annotations collected using the Neibhour Enrichment function in STRING, which includes annotations from nearest neighbour proteins to the input target. The predictive features in this dataset refer only to category of protein domains sourced from InterPro. Special Columns: Category Description Index ID Unique identifier for the compound/sex combination (instance) in the data. Ignored when training the classification model. Compound_name ID Name of the compound (drug). Ignored when training the classification model. class Target Variable Class label, with 0 indicating that the drug/sex combination is NOT associated with mouse longevity, and 1 indicating that it IS associated with mouse longevity, based on results from peer-reviewed studies. Predictive Features: Category Description IPR000276 InterPro G protein-coupled receptor, rhodopsin-like IPR017452 InterPro GPCR, rhodopsin-like, 7TM IPR000286 InterPro Histone deacetylase family IPR003084 InterPro Histone deacetylase IPR023696 InterPro Ureohydrolase domain superfamily IPR023801 InterPro Histone deacetylase domain IPR037138 InterPro Histone deacetylase domain superfamily IPR017320 InterPro Histone deacetylase class II, eukaryotic-type IPR024643 InterPro Histone deacetylase, glutamine rich N-terminal domain IPR046949 InterPro Histone deacetylase 4/5/7/9 IPR000536 InterPro Nuclear hormone receptor, ligand-binding domain IPR001628 InterPro Zinc finger, nuclear hormone receptor-type IPR013088 InterPro Zinc finger, NHR/GATA-type IPR035500 InterPro Nuclear hormone receptor-like domain superfamily IPR001103 InterPro Androgen receptor IPR001723 InterPro Nuclear hormone receptor IPR024178 InterPro Estrogen receptor/oestrogen-related receptor IPR001292 InterPro Estrogen receptor IPR024736 InterPro Oestrogen-type nuclear receptor final C-terminal domain IPR046944 InterPro Estrogen receptor, N-terminal IPR021064 InterPro Estrogen receptor beta-like, N-terminal IPR028355 InterPro Estrogen receptor beta/gamma IPR001404 InterPro Heat shock protein Hsp90 family IPR003594 InterPro Histidine kinase/HSP90-like ATPase IPR019805 InterPro Heat shock protein Hsp90, conserved site IPR020568 InterPro Ribosomal protein S5 domain 2-type fold IPR020575 InterPro Heat shock protein Hsp90, N-terminal IPR036890 InterPro Histidine kinase/HSP90-like ATPase superfamily IPR037196 InterPro HSP90, C-terminal domain IPR000014 InterPro PAS domain IPR001610 InterPro PAC motif IPR011598 InterPro Myc-type, basic helix-loop-helix (bHLH) domain IPR013655 InterPro PAS fold-3 IPR013767 InterPro PAS fold IPR035965 InterPro PAS domain superfamily IPR036638 InterPro Helix-loop-helix DNA-binding domain superfamily IPR001102 InterPro Transglutaminase, N-terminal IPR002931 InterPro Transglutaminase-like IPR008958 InterPro Transglutaminase, C-terminal IPR013783 InterPro Immunoglobulin-like fold IPR013808 InterPro Transglutaminase, active site IPR014756 InterPro Immunoglobulin E-set IPR023608 InterPro Protein-glutamine gamma-glutamyltransferase, animal IPR036238 InterPro Transglutaminase, C-terminal domain superfamily IPR036985 InterPro Transglutaminase-like superfamily IPR038765 InterPro Papain-like cysteine peptidase superfamily IPR001309 InterPro Peptidase C14, p20 domain IPR002138 InterPro Peptidase C14, caspase non-catalytic subunit p10 IPR002398 InterPro Peptidase C14 family IPR011600 InterPro Peptidase C14, caspase domain IPR015917 InterPro Peptidase C14A, caspase catalytic domain IPR016129 InterPro Peptidase family C14A, His active site IPR029030 InterPro Caspase-like domain superfamily IPR033139 InterPro Peptidase family C14A, cysteine active site IPR013083 InterPro Zinc finger, RING/FYVE/PHD-type IPR003193 InterPro ADP-ribosyl cyclase (CD38/157) IPR017853 InterPro Glycoside hydrolase superfamily IPR000742 InterPro EGF-like domain IPR010255 InterPro Haem peroxidase superfamily IPR019791 InterPro Haem peroxidase, animal-type IPR037120 InterPro Haem peroxidase domain superfamily, animal type IPR002110 InterPro Ankyrin repeat IPR005821 InterPro Ion transport domain IPR036770 InterPro Ankyrin repeat-containing domain superfamily IPR000175 InterPro Sodium:neurotransmitter symporter IPR037272 InterPro Sodium:neurotransmitter symporter superfamily IPR013086 InterPro Sodium:neurotransmitter symporter, serotonin, N-terminal IPR000341 InterPro Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain IPR000403 InterPro Phosphatidylinositol 3-/4-kinase, catalytic domain IPR001263 InterPro Phosphoinositide 3-kinase, accessory (PIK) domain IPR002420 InterPro C2 phosphatidylinositol 3-kinase-type domain IPR003113 InterPro Phosphatidylinositol 3-kinase, adaptor-binding domain IPR011009 InterPro Protein kinase-like domain superfamily IPR015433 InterPro Phosphatidylinositol kinase IPR016024 InterPro Armadillo-type fold IPR018936 InterPro Phosphatidylinositol 3/4-kinase, conserved site IPR029071 InterPro Ubiquitin-like domain superfamily IPR035892 InterPro C2 domain superfamily IPR036940 InterPro Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily IPR042236 InterPro Phosphoinositide 3-kinase, accessory (PIK) domain superfamily IPR045580 InterPro PIK3 catalytic subunit gamma, adaptor-binding domain IPR002893 InterPro Zinc finger, MYND-type IPR005123 InterPro Oxoglutarate/iron-dependent dioxygenase IPR006620 InterPro Prolyl 4-hydroxylase, alpha subunit IPR044862 InterPro Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain IPR045864 InterPro Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) IPR001734 InterPro Sodium/solute symporter IPR018212 InterPro Sodium/solute symporter, conserved site IPR038377 InterPro Sodium/glucose symporter superfamily IPR013785 InterPro Aldolase-type TIM barrel IPR006095 InterPro Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase IPR006096 InterPro Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal IPR006097 InterPro Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain IPR033524 InterPro Leu/Phe/Val dehydrogenases active site IPR033922 InterPro NAD(P) binding domain of glutamate dehydrogenase IPR036291 InterPro NAD(P)-binding domain superfamily IPR046346 InterPro Aminoacid dehydrogenase-like, N-terminal domain superfamily IPR011990 InterPro Tetratricopeptide-like helical domain superfamily IPR019734 InterPro Tetratricopeptide repeat IPR002048 InterPro EF-hand domain IPR011992 InterPro EF-hand domain pair IPR018247 InterPro EF-Hand 1, calcium-binding site IPR006043 InterPro Nucleobase cation symporter 2 family IPR006042 InterPro Xanthine/uracil permease IPR002233 InterPro Adrenoceptor family IPR000719 InterPro Protein kinase domain IPR008271 InterPro Serine/threonine-protein kinase, active site IPR017441 InterPro Protein kinase, ATP binding site IPR028375 InterPro KA1 domain/Ssp2, C-terminal IPR032270 InterPro AMPK, C-terminal adenylate sensor domain IPR028797 InterPro PRKAA1, UBA-like autoinhibitory domain IPR039137 InterPro 5-AMP-activated protein kinase alpha 1 catalytic subunit, C-terminal IPR028783 InterPro PRKAA2, UBA-like autoinhibitory domain IPR039148 InterPro 5-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal IPR006828 InterPro Association with the SNF1 complex (ASC) domain IPR032640 InterPro AMP-activated protein kinase, glycogen-binding domain IPR037256 InterPro ASC domain superfamily IPR000644 InterPro CBS domain IPR003527 InterPro Mitogen-activated protein (MAP) kinase, conserved site IPR008349 InterPro Mitogen-activated protein (MAP) kinase, ERK1/2 IPR008350 InterPro Mitogen-activated protein (MAP) kinase, ERK3/4 IPR018170 InterPro Aldo/keto reductase, conserved site IPR020471 InterPro Aldo-keto reductase IPR023210 InterPro NADP-dependent oxidoreductase domain IPR036812 InterPro NADP-dependent oxidoreductase domain superfamily IPR044482 InterPro Aldo-keto reductase family 1 member C IPR008967 InterPro p53-like transcription factor, DNA-binding domain superfamily IPR013126 InterPro Heat shock protein 70 family IPR018181 InterPro Heat shock protein 70, conserved site IPR029047 InterPro Heat shock protein 70kD, peptide-binding domain superfamily IPR029048 InterPro Heat shock protein 70kD, C-terminal domain superfamily IPR043129 InterPro ATPase, nucleotide binding domain IPR000961 InterPro AGC-kinase, C-terminal IPR017892 InterPro Protein kinase, C-terminal IPR016186 InterPro C-type lectin-like/link domain superfamily IPR016187 InterPro C-type lectin fold IPR001315 InterPro CARD domain IPR011029 InterPro Death-like domain superfamily IPR000626 InterPro Ubiquitin-like domain IPR022007 InterPro I-kappa-kinase-beta NEMO binding domain IPR041185 InterPro IKBKB, scaffold dimerization domain IPR046375 InterPro IKBKB, scaffold dimerization domain superfamily IPR000451 InterPro NF-kappa-B/Dorsal IPR000488 InterPro Death domain IPR002909 InterPro IPT domain IPR011539 InterPro Rel homology domain, DNA-binding domain IPR030492 InterPro Rel homology domain, conserved site IPR032397 InterPro Rel homology dimerisation domain IPR033926 InterPro NFkappaB IPT domain IPR037059 InterPro Rel homology domain (RHD), DNA-binding domain superfamily IPR030497 InterPro Nuclear factor NF-kappa-B, p100 subunit, RHD domain, N-terminal IPR030503 InterPro Nuclear factor NF-kappa-B, p105 subunit, Rel homology domain, N-terminal IPR047096 InterPro Nuclear factor NF-kappa-B p105 subunit, death domain IPR000997 InterPro Cholinesterase IPR002018 InterPro Carboxylesterase, type B IPR014788 InterPro Acetylcholinesterase, tetramerisation domain IPR019819 InterPro Carboxylesterase type B, conserved site IPR019826 InterPro Carboxylesterase type B, active site IPR029058 InterPro Alpha/Beta hydrolase fold IPR000555 InterPro JAB1/MPN/MOV34 metalloenzyme domain IPR037518 InterPro MPN domain IPR006716 InterPro ERG2/sigma1 receptor-like IPR000595 InterPro Cyclic nucleotide-binding domain IPR000700 InterPro PAS-associated, C-terminal IPR003938 InterPro Potassium channel, voltage-dependent, EAG/ELK/ERG IPR003967 InterPro Potassium channel, voltage-dependent, ERG IPR014710 InterPro RmlC-like jelly roll fold IPR018490 InterPro Cyclic nucleotide-binding domain superfamily IPR001128 InterPro Cytochrome P450 IPR002401 InterPro Cytochrome P450, E-class, group I IPR017972 InterPro Cytochrome P450, conserved site IPR036396 InterPro Cytochrome P450 superfamily IPR002350 InterPro Kazal domain IPR004156 InterPro Organic anion transporter polypeptide IPR020846 InterPro Major facilitator superfamily domain IPR036058 InterPro Kazal domain superfamily IPR036259 InterPro MFS transporter superfamily IPR000749 InterPro ATP:guanido phosphotransferase IPR014746 InterPro Glutamine synthetase/guanido kinase, catalytic domain IPR022413 InterPro ATP:guanido phosphotransferase, N-terminal IPR022414 InterPro ATP:guanido phosphotransferase, catalytic domain IPR022415 InterPro ATP:guanido phosphotransferase active site IPR036802 InterPro ATP:guanido phosphotransferase, N-terminal domain superfamily IPR001148 InterPro Alpha carbonic anhydrase domain IPR018338 InterPro Carbonic anhydrase, alpha-class, conserved site IPR023561 InterPro Carbonic anhydrase, alpha-class IPR036398 InterPro Alpha carbonic anhydrase domain superfamily IPR030495 InterPro Transcription factor p65, RHD domain, N-terminal IPR000907 InterPro Lipoxygenase IPR001024 InterPro PLAT/LH2 domain IPR001885 InterPro Lipoxygenase, mammalian IPR013819 InterPro Lipoxygenase, C-terminal IPR020833 InterPro Lipoxygenase, iron binding site IPR020834 InterPro Lipoxygenase, conserved site IPR036226 InterPro Lipoxigenase, C-terminal domain superfamily IPR036392 InterPro PLAT/LH2 domain superfamily IPR042062 InterPro Lipoxygenase, vertebrates, PLAT domain IPR001548 InterPro Peptidase M2, peptidyl-dipeptidase A IPR000562 InterPro Fibronectin type II domain IPR000585 InterPro Hemopexin-like domain IPR001818 InterPro Peptidase M10, metallopeptidase IPR002477 InterPro Peptidoglycan binding-like IPR006026 InterPro Peptidase, metallopeptidase IPR013806 InterPro Kringle-like fold IPR018486 InterPro Hemopexin, conserved site IPR018487 InterPro Hemopexin-like repeats IPR021158 InterPro Peptidase M10A, cysteine switch, zinc binding site IPR021190 InterPro Peptidase M10A IPR024079 InterPro Metallopeptidase, catalytic domain superfamily IPR033739 InterPro Peptidase M10A, catalytic domain IPR036365 InterPro PGBD-like superfamily IPR036375 InterPro Hemopexin-like domain superfamily IPR036943 InterPro Fibronectin type II domain superfamily IPR000001 InterPro Kringle IPR000294 InterPro Gamma-carboxyglutamic acid-rich (GLA) domain IPR001254 InterPro Serine proteases, trypsin domain IPR001314 InterPro Peptidase S1A, chymotrypsin family IPR009003 InterPro Peptidase S1, PA clan IPR018056 InterPro Kringle, conserved site IPR018114 InterPro Serine proteases, trypsin family, histidine active site IPR033116 InterPro Serine proteases, trypsin family, serine active site IPR035972 InterPro Gamma-carboxyglutamic acid-rich (GLA) domain superfamily IPR038178 InterPro Kringle superfamily IPR043504 InterPro Peptidase S1, PA clan, chymotrypsin-like fold IPR003966 InterPro Prothrombin/thrombin IPR018992 InterPro Thrombin light chain IPR037111 InterPro Thrombin light chain domain superfamily IPR001806 InterPro Small GTPase IPR005225 InterPro Small GTP-binding protein domain IPR027417 InterPro P-loop containing nucleoside triphosphate hydrolase IPR004045 InterPro Glutathione S-transferase, N-terminal IPR004046 InterPro Glutathione S-transferase, C-terminal IPR010987 InterPro Glutathione S-transferase, C-terminal-like IPR036249 InterPro Thioredoxin-like superfamily IPR036282 InterPro Glutathione S-transferase, C-terminal domain superfamily IPR040079 InterPro Glutathione transferase family IPR006052 InterPro Tumour necrosis factor domain IPR006053 InterPro Tumour necrosis factor IPR008983 InterPro Tumour necrosis factor-like domain superfamily IPR021184 InterPro Tumour necrosis factor, conserved site IPR002959 InterPro Tumour necrosis factor alpha IPR001611 InterPro Leucine-rich repeat IPR032675 InterPro Leucine-rich repeat domain superfamily IPR000921 InterPro Histamine H1 receptor IPR002435 InterPro Sodium:neurotransmitter symporter, noradrenaline IPR008066 InterPro Cytochrome P450, E-class, group I, CYP1 IPR003439 InterPro ABC transporter-like, ATP-binding domain IPR003593 InterPro AAA+ ATPase domain IPR011527 InterPro ABC transporter type 1, transmembrane domain IPR017871 InterPro ABC transporter-like, conserved site IPR036640 InterPro ABC transporter type 1, transmembrane domain superfamily IPR000674 InterPro Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead IPR001041 InterPro 2Fe-2S ferredoxin-type iron-sulfur binding domain IPR002346 InterPro Molybdopterin dehydrogenase, FAD-binding IPR002888 InterPro [2Fe-2S]-binding IPR005107 InterPro CO dehydrogenase flavoprotein, C-terminal IPR006058 InterPro 2Fe-2S ferredoxin, iron-sulphur binding site IPR008274 InterPro Aldehyde oxidase/xanthine dehydrogenase, first molybdopterin binding domain IPR012675 InterPro Beta-grasp domain superfamily IPR016166 InterPro FAD-binding domain, PCMH-type IPR016167 InterPro FAD-binding, type PCMH, subdomain 1 IPR016169 InterPro FAD-binding, type PCMH, subdomain 2 IPR016208 InterPro Aldehyde oxidase/xanthine dehydrogenase IPR022407 InterPro Oxidoreductase, molybdopterin binding site IPR036010 InterPro 2Fe-2S ferredoxin-like superfamily IPR036318 InterPro FAD-binding, type PCMH-like superfamily IPR036683 InterPro CO dehydrogenase flavoprotein, C-terminal domain superfamily IPR036856 InterPro Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily IPR036884 InterPro [2Fe-2S]-binding domain superfamily IPR037165 InterPro Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily IPR046867 InterPro Aldehyde oxidase/xanthine dehydrogenase, second molybdopterin binding domain IPR026193 InterPro NADH-ubiquinone oxidoreductase flavoprotein 3 IPR036188 InterPro FAD/NAD(P)-binding domain superfamily IPR003952 InterPro Fumarate reductase/succinate dehydrogenase, FAD-binding site IPR003953 InterPro FAD-dependent oxidoreductase 2, FAD binding domain IPR011281 InterPro Succinate dehydrogenase, flavoprotein subunit IPR014006 InterPro Succinate dehydrogenase/fumarate reductase, flavoprotein subunit IPR015939 InterPro Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal IPR027477 InterPro Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily IPR030664 InterPro FAD-dependent oxidoreductase SdhA/FrdA/AprA IPR037099 InterPro Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily IPR029063 InterPro S-adenosyl-L-methionine-dependent methyltransferase superfamily IPR003074 InterPro Peroxisome proliferator-activated receptor IPR003077 InterPro Peroxisome proliferator-activated receptor gamma IPR022590 InterPro Peroxisome proliferator-activated receptor gamma, N-terminal IPR002347 InterPro Short-chain dehydrogenase/reductase SDR IPR020904 InterPro Short-chain dehydrogenase/reductase, conserved site IPR045313 InterPro Carbonyl reductase [NADPH] 1-like IPR002223 InterPro Pancreatic trypsin inhibitor Kunitz domain IPR008154 InterPro Amyloidogenic glycoprotein, extracellular IPR008155 InterPro Amyloidogenic glycoprotein IPR011178 InterPro Amyloidogenic glycoprotein, copper-binding IPR011993 InterPro PH-like domain superfamily IPR015849 InterPro Amyloidogenic glycoprotein, heparin-binding IPR019543 InterPro Beta-amyloid precursor protein C-terminal IPR019744 InterPro Amyloidogenic glycoprotein, copper-binding domain conserved site IPR019745 InterPro Amyloidogenic glycoprotein, intracellular domain, conserved site IPR020901 InterPro Proteinase inhibitor I2, Kunitz, conserved site IPR024329 InterPro Amyloidogenic glycoprotein, E2 domain IPR036176 InterPro E2 domain superfamily IPR036454 InterPro Amyloidogenic glycoprotein, heparin-binding domain superfamily IPR036669 InterPro Amyloidogenic glycoprotein, copper-binding domain superfamily IPR036880 InterPro Pancreatic trypsin inhibitor Kunitz domain superfamily IPR013803 InterPro Amyloidogenic glycoprotein, amyloid-beta peptide IPR037071 InterPro Amyloidogenic glycoprotein, amyloid-beta peptide superfamily IPR003961 InterPro Fibronectin type III IPR036116 InterPro Fibronectin type III superfamily IPR004839 InterPro Aminotransferase, class I/classII IPR015421 InterPro Pyridoxal phosphate-dependent transferase, major domain IPR015422 InterPro Pyridoxal phosphate-dependent transferase, small domain IPR015424 InterPro Pyridoxal phosphate-dependent transferase IPR009080 InterPro Aminoacyl-tRNA synthetase, class Ia, anticodon-binding IPR014729 InterPro Rossmann-like alpha/beta/alpha sandwich fold IPR036388 InterPro Winged helix-like DNA-binding domain superfamily IPR016185 InterPro Pre-ATP-grasp domain superfamily IPR004887 InterPro Glutathione synthase, substrate-binding domain IPR005615 InterPro Glutathione synthase IPR014042 InterPro Glutathione synthase, alpha-helical IPR014049 InterPro Glutathione synthase, N-terminal, eukaryotic IPR014709 InterPro Glutathione synthase, C-terminal, eukaryotic IPR037013 InterPro Glutathione synthase, substrate-binding domain superfamily IPR000192 InterPro Aminotransferase class V domain IPR020578 InterPro Aminotransferase class-V, pyridoxal-phosphate binding site IPR001390 InterPro Gamma-aminobutyric-acid A receptor, alpha subunit IPR006028 InterPro Gamma-aminobutyric acid A receptor/Glycine receptor alpha IPR006029 InterPro Neurotransmitter-gated ion-channel transmembrane domain IPR006201 InterPro Neurotransmitter-gated ion-channel IPR006202 InterPro Neurotransmitter-gated ion-channel ligand-binding domain IPR018000 InterPro Neurotransmitter-gated ion-channel, conserved site IPR036719 InterPro Neurotransmitter-gated ion-channel transmembrane domain superfamily IPR036734 InterPro Neurotransmitter-gated ion-channel ligand-binding domain superfamily IPR038050 InterPro Neuronal acetylcholine receptor IPR047024 InterPro Gamma-aminobutyric acid receptor subunit alpha 1-6, transmembrane domain IPR005431 InterPro Gamma-aminobutyric-acid A receptor, alpha 1 subunit IPR047079 InterPro Gamma-aminobutyric acid receptor subunit alpha-1, extracellular domain IPR005432 InterPro Gamma-aminobutyric-acid A receptor, alpha 2 subunit IPR047023 InterPro Gamma-aminobutyric acid receptor subunit alpha-2, extracellular domain IPR005433 InterPro Gamma-aminobutyric-acid A receptor, alpha 3 subunit IPR005434 InterPro Gamma-aminobutyric-acid A receptor, alpha 4 subunit IPR005435 InterPro Gamma-aminobutyric-acid A receptor, alpha 5 subunit IPR005436 InterPro Gamma-aminobutyric-acid A receptor, alpha 6 subunit IPR002289 InterPro Gamma-aminobutyric-acid A receptor, beta subunit IPR008098 InterPro Gamma-aminobutyric-acid A receptor delta subunit IPR008099 InterPro Gamma-aminobutyric-acid A receptor epsilon subunit IPR005437 InterPro Gamma-aminobutyric acid receptor subunit gamma-1/4 IPR005438 InterPro Gamma-aminobutyric-acid A receptor, gamma 1 subunit IPR005439 InterPro Gamma-aminobutyric-acid A receptor, gamma 2 subunit IPR005440 InterPro Gamma-aminobutyric-acid A receptor, gamma 3 subunit IPR008100 InterPro Gamma-aminobutyric-acid A receptor pi subunit IPR047032 InterPro Gamma-aminobutyric acid receptor subunit pi, transmembrane domain IPR008101 InterPro Gamma-aminobutyric-acid A receptor theta subunit IPR001320 InterPro Ionotropic glutamate receptor, C-terminal IPR001508 InterPro Ionotropic glutamate receptor, metazoa IPR001828 InterPro Receptor, ligand binding region IPR015683 InterPro Ionotropic glutamate receptor IPR019594 InterPro Ionotropic glutamate receptor, L-glutamate and glycine-binding domain IPR028082 InterPro Periplasmic binding protein-like I IPR018882 InterPro Calmodulin-binding domain C0, NMDA receptor, NR1 subunit IPR018884 InterPro Glutamate [NMDA] receptor, epsilon subunit, C-terminal IPR003076 InterPro Peroxisome proliferator-activated receptor alpha IPR001728 InterPro Thyroid hormone receptor IPR001791 InterPro Laminin G domain IPR013320 InterPro Concanavalin A-like lectin/glucanase domain superfamily IPR015915 InterPro Kelch-type beta propeller IPR001031 InterPro Thioesterase IPR001227 InterPro Acyl transferase domain superfamily IPR006162 InterPro Phosphopantetheine attachment site IPR009081 InterPro Phosphopantetheine binding ACP domain IPR011032 InterPro GroES-like superfamily IPR013149 InterPro Alcohol dehydrogenase-like, C-terminal IPR013217 InterPro Methyltransferase type 12 IPR014030 InterPro Beta-ketoacyl synthase, N-terminal IPR014031 InterPro Beta-ketoacyl synthase, C-terminal IPR014043 InterPro Acyl transferase IPR016035 InterPro Acyl transferase/acyl hydrolase/lysophospholipase IPR016036 InterPro Malonyl-CoA ACP transacylase, ACP-binding IPR016039 InterPro Thiolase-like IPR018201 InterPro Beta-ketoacyl synthase, active site IPR020841 InterPro Polyketide synthase, beta-ketoacyl synthase domain IPR020843 InterPro Polyketide synthase, enoylreductase domain IPR036736 InterPro ACP-like superfamily IPR013968 InterPro Polyketide synthase, ketoreductase domain IPR020806 InterPro Polyketide synthase, phosphopantetheine-binding domain IPR020807 InterPro Polyketide synthase, dehydratase domain IPR032821 InterPro Polyketide synthase, C-terminal extension IPR042104 InterPro Polyketide synthase, dehydratase domain superfamily IPR006076 InterPro FAD dependent oxidoreductase IPR008127 InterPro Glycine receptor alpha IPR008128 InterPro Glycine receptor alpha1 IPR008060 InterPro Glycine receptor beta IPR047029 InterPro Glycine receptor subunit beta, transmembrane domain IPR047031 InterPro Glycine receptor subunit beta, extracellular domain IPR008130 InterPro Glycine receptor alpha3 IPR008129 InterPro Glycine receptor alpha2 IPR000089 InterPro Biotin/lipoyl attachment IPR011053 InterPro Single hybrid motif IPR000068 InterPro GPCR, family 3, extracellular calcium-sensing receptor-related IPR000337 InterPro GPCR, family 3 IPR011500 InterPro GPCR, family 3, nine cysteines domain IPR017978 InterPro GPCR family 3, C-terminal IPR017979 InterPro GPCR, family 3, conserved site IPR038550 InterPro GPCR, family 3, nine cysteines domain superfamily IPR000725 InterPro Olfactory receptor IPR041890 InterPro Carbonic anhydrase VII IPR041874 InterPro Carbonic anhydrase, CA4/CA15 IPR034804 InterPro Fumarate reductase/succinate dehydrogenase, transmembrane subunit IPR007992 InterPro Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, CybS IPR001245 InterPro Serine-threonine/tyrosine-protein kinase, catalytic domain IPR008266 InterPro Tyrosine-protein kinase, active site IPR020635 InterPro Tyrosine-protein kinase, catalytic domain IPR044114 InterPro Bile acid receptor, ligand binding domain IPR001613 InterPro Flavin amine oxidase IPR002937 InterPro Amine oxidase IPR001058 InterPro Synuclein IPR002460 InterPro Alpha-synuclein IPR001094 InterPro Flavodoxin-like IPR001433 InterPro Oxidoreductase FAD/NAD(P)-binding IPR001709 InterPro Flavoprotein pyridine nucleotide cytochrome reductase IPR003097 InterPro Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding IPR008254 InterPro Flavodoxin/nitric oxide synthase IPR017927 InterPro FAD-binding domain, ferredoxin reductase-type IPR017938 InterPro Riboflavin synthase-like beta-barrel IPR023173 InterPro NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily IPR029039 InterPro Flavoprotein-like superfamily IPR039261 InterPro Ferredoxin-NADP reductase (FNR), nucleotide-binding domain IPR036390 InterPro Winged helix DNA-binding domain superfamily IPR003980 InterPro Histamine H3 receptor IPR000025 InterPro Melatonin receptor family IPR002278 InterPro Melatonin receptor 1A/1B IPR003680 InterPro Flavodoxin-like fold IPR017896 InterPro 4Fe-4S ferredoxin-type, iron-sulphur binding domain IPR017900 InterPro 4Fe-4S ferredoxin, iron-sulphur binding, conserved site IPR029045 InterPro ClpP/crotonase-like domain superfamily IPR000507 InterPro Beta 1 adrenoceptor IPR000332 InterPro Beta 2 adrenoceptor IPR008996 InterPro Cytokine IL1/FGF IPR005828 InterPro Major facilitator, sugar transporter-like IPR003000 InterPro Sirtuin family IPR026590 InterPro Sirtuin family, catalytic core domain IPR026591 InterPro Sirtuin, catalytic core small domain superfamily IPR029035 InterPro DHS-like NAD/FAD-binding domain superfamily IPR004166 InterPro MHCK/EF2 kinase IPR032415 InterPro TRPM, tetramerisation domain IPR037162 InterPro TRPM, tetramerisation domain superfamily IPR041491 InterPro TRPM, SLOG domain IPR029601 InterPro Transient receptor potential cation channel subfamily M member 7, alpha-kinase domain IPR000826 InterPro Formyl peptide receptor-related IPR015943 InterPro WD40/YVTN repeat-like-containing domain superfamily IPR036322 InterPro WD40-repeat-containing domain superfamily IPR001849 InterPro Pleckstrin homology domain IPR039026 InterPro Protein Kinase B, pleckstrin homology domain IPR034676 InterPro Protein kinase B alpha, catalytic domain IPR013518 InterPro Potassium channel, inwardly rectifying, Kir, cytoplasmic IPR016449 InterPro Potassium channel, inwardly rectifying, Kir IPR040445 InterPro Potassium channel, inwardly rectifying, transmembrane domain IPR041647 InterPro Inward rectifier potassium channel, C-terminal IPR013673 InterPro Potassium channel, inwardly rectifying, Kir, N-terminal IPR003271 InterPro Potassium channel, inwardly rectifying, Kir2.1 IPR033348 InterPro Aryl hydrocarbon receptor, basic helix-loop-helix domain IPR045216 InterPro Casein Kinase 2, subunit alpha IPR000413 InterPro Integrin alpha chain IPR013517 InterPro FG-GAP repeat IPR013519 InterPro Integrin alpha beta-propellor IPR013649 InterPro Integrin alpha-2 IPR018184 InterPro Integrin alpha chain, C-terminal cytoplasmic region, conserved site IPR028994 InterPro Integrin alpha, N-terminal IPR032695 InterPro Integrin domain superfamily IPR002369 InterPro Integrin beta subunit, VWA domain IPR012896 InterPro Integrin beta subunit, tail IPR014836 InterPro Integrin beta subunit, cytoplasmic domain IPR015812 InterPro Integrin beta subunit IPR016201 InterPro PSI domain IPR033760 InterPro Integrin beta N-terminal IPR036349 InterPro Integrin beta tail domain superfamily IPR036465 InterPro Von Willebrand factor A-like domain superfamily