Data Description file for Dataset: Neighbour Enrichment - WikiPathways Description: Dataset of target annotations collected using the Neibhour Enrichment function in STRING, which includes annotations from nearest neighbour proteins to the input target. The predictive features in this dataset refer only to category of Pathways sourced from WikiPathways. Special Columns: Category Description Index ID Unique identifier for the compound/sex combination (instance) in the data. Ignored when training the classification model. Compound_name ID Name of the compound (drug). Ignored when training the classification model. class Target Variable Class label, with 0 indicating that the drug/sex combination is NOT associated with mouse longevity, and 1 indicating that it IS associated with mouse longevity, based on results from peer-reviewed studies. Predictive Features: Category Description WP4320 WikiPathways Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome WP3651 WikiPathways Pathways affected in adenoid cystic carcinoma WP138 WikiPathways Androgen receptor signaling pathway WP179 WikiPathways Cell cycle WP3594 WikiPathways Circadian rhythm genes WP61 WikiPathways Notch signaling pathway WP2261 WikiPathways Glioblastoma signaling pathways WP2446 WikiPathways Retinoblastoma gene in cancer WP399 WikiPathways Wnt signaling pathway and pluripotency WP5049 WikiPathways Glycolysis in senescence WP366 WikiPathways TGF-beta signaling pathway WP5046 WikiPathways NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence WP3414 WikiPathways Initiation of transcription and translation elongation at the HIV-1 LTR WP5097 WikiPathways CCL18 signaling pathway WP2828 WikiPathways Bladder cancer WP1541 WikiPathways Energy metabolism WP1971 WikiPathways Integrated cancer pathway WP2586 WikiPathways Aryl hydrocarbon receptor pathway WP268 WikiPathways Notch signaling WP3611 WikiPathways Photodynamic therapy-induced AP-1 survival signaling WP4312 WikiPathways Rett syndrome causing genes WP4879 WikiPathways Overlap between signal transduction pathways contributing to LMNA laminopathies WP304 WikiPathways Kit receptor signaling pathway WP3998 WikiPathways Prader-Willi and Angelman syndrome WP45 WikiPathways G1 to S cell cycle control WP4685 WikiPathways Melanoma WP707 WikiPathways DNA damage response WP1530 WikiPathways miRNA regulation of DNA damage response WP3584 WikiPathways MECP2 and associated Rett syndrome WP4255 WikiPathways Non-small cell lung cancer WP4674 WikiPathways Head and neck squamous cell carcinoma WP4263 WikiPathways Pancreatic adenocarcinoma pathway WP4658 WikiPathways Small cell lung cancer WP2064 WikiPathways Neural crest differentiation WP5087 WikiPathways Malignant pleural mesothelioma WP2263 WikiPathways Androgen receptor network in prostate cancer WP2431 WikiPathways Spinal cord injury WP5322 WikiPathways CKAP4 signaling pathway map WP4657 WikiPathways 22q11.2 copy number variation syndrome WP236 WikiPathways Adipogenesis WP2916 WikiPathways Interactome of polycomb repressive complex 2 (PRC2) WP4533 WikiPathways Transcription co-factors SKI and SKIL protein partners WP4204 WikiPathways Tumor suppressor activity of SMARCB1 WP2023 WikiPathways Cell differentiation - expanded index WP2029 WikiPathways Cell differentiation - index WP2795 WikiPathways Cardiac hypertrophic response WP474 WikiPathways Endochondral ossification WP4808 WikiPathways Endochondral ossification with skeletal dysplasias WP1991 WikiPathways SRF and miRs in smooth muscle differentiation and proliferation WP5224 WikiPathways 2q37 copy number variation syndrome WP3888 WikiPathways VEGFA-VEGFR2 signaling WP3996 WikiPathways Ethanol effects on histone modifications WP1544 WikiPathways MicroRNAs in cardiomyocyte hypertrophy WP3981 WikiPathways miRNA regulation of prostate cancer signaling pathways WP2876 WikiPathways Pregnane X receptor pathway WP2355 WikiPathways Corticotropin-releasing hormone signaling pathway WP2882 WikiPathways Nuclear receptors meta-pathway WP3932 WikiPathways Focal adhesion: PI3K-Akt-mTOR-signaling pathway WP4746 WikiPathways Thyroid hormones production and peripheral downstream signaling effects WP2875 WikiPathways Constitutive androstane receptor pathway WP4262 WikiPathways Breast cancer pathway WP712 WikiPathways Estrogen signaling pathway WP2873 WikiPathways Aryl hydrocarbon receptor pathway WP437 WikiPathways EGF/EGFR signaling pathway WP2881 WikiPathways Estrogen receptor pathway WP2034 WikiPathways Leptin signaling pathway WP4659 WikiPathways Gastrin signaling pathway WP313 WikiPathways Hepatocyte growth factor receptor signaling WP2526 WikiPathways PDGF pathway WP286 WikiPathways IL-3 signaling pathway WP2018 WikiPathways RANKL/RANK signaling pathway WP5235 WikiPathways Estradiol regulation in porto-sinusoidal vascular disease WP2032 WikiPathways Thyroid stimulating hormone (TSH) signaling pathway WP2324 WikiPathways AGE/RAGE pathway WP5130 WikiPathways Th17 cell differentiation pathway WP2037 WikiPathways Prolactin signaling pathway WP2814 WikiPathways Mammary gland development pathway - Puberty (Stage 2 of 4) WP4919 WikiPathways Neuroinflammation WP2435 WikiPathways Quercetin and Nf-kB / AP-1 induced apoptosis WP4928 WikiPathways MAPK pathway in congenital thyroid cancer WP2380 WikiPathways Brain-derived neurotrophic factor (BDNF) signaling pathway WP4666 WikiPathways Hepatitis B infection WP289 WikiPathways Myometrial relaxation and contraction pathways WP3612 WikiPathways Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling WP1528 WikiPathways Physiological and pathological hypertrophy of the heart WP4483 WikiPathways Relationship between inflammation, COX-2 and EGFR WP3972 WikiPathways PDGFR-beta pathway WP408 WikiPathways Oxidative stress response WP4880 WikiPathways Host-pathogen interaction of human coronaviruses - interferon induction WP4877 WikiPathways Host-pathogen interaction of human coronaviruses - MAPK signaling WP34 WikiPathways Ovarian infertility WP5269 WikiPathways Genetic causes of porto-sinusoidal vascular disease WP4564 WikiPathways Neural crest cell migration during development WP127 WikiPathways IL-5 signaling pathway WP4565 WikiPathways Neural crest cell migration in cancer WP49 WikiPathways IL-2 signaling pathway WP5300 WikiPathways TROP2 regulatory signaling WP3286 WikiPathways Copper homeostasis WP4747 WikiPathways Netrin-UNC5B signaling pathway WP4754 WikiPathways IL-18 signaling pathway WP560 WikiPathways TGF-beta receptor signaling WP4205 WikiPathways MET in type 1 papillary renal cell carcinoma WP4816 WikiPathways TGF-beta receptor signaling in skeletal dysplasias WP3863 WikiPathways T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection WP2374 WikiPathways Oncostatin M signaling pathway WP3680 WikiPathways Physico-chemical features and toxicity-associated pathways WP2880 WikiPathways Glucocorticoid receptor pathway WP4216 WikiPathways Chromosomal and microsatellite instability in colorectal cancer WP4341 WikiPathways Non-genomic actions of 1,25 dihydroxyvitamin D3 WP2840 WikiPathways Hair follicle development: cytodifferentiation - part 3 of 3 WP5098 WikiPathways T-cell activation SARS-CoV-2 WP1772 WikiPathways Apoptosis modulation and signaling WP673 WikiPathways ErbB signaling pathway WP69 WikiPathways T-cell receptor signaling pathway WP231 WikiPathways TNF-alpha signaling pathway WP75 WikiPathways Toll-like receptor signaling pathway WP3931 WikiPathways Embryonic stem cell pluripotency pathways WP4630 WikiPathways Measles virus infection WP706 WikiPathways Sudden infant death syndrome (SIDS) susceptibility pathways WP481 WikiPathways Insulin signaling WP2817 WikiPathways Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4) WP5316 WikiPathways Primary ovarian insufficiency WP306 WikiPathways Focal adhesion WP170 WikiPathways Nuclear receptors WP4545 WikiPathways Oxysterols derived from cholesterol WP4298 WikiPathways Acute viral myocarditis WP185 WikiPathways Integrin-mediated cell adhesion WP4673 WikiPathways Male infertility WP4155 WikiPathways Endometrial cancer WP3303 WikiPathways RAC1/PAK1/p38/MMP2 pathway WP4172 WikiPathways PI3K-Akt signaling pathway WP2363 WikiPathways Gastric cancer network 2 WP2870 WikiPathways Extracellular vesicle-mediated signaling in recipient cells WP4949 WikiPathways 16p11.2 proximal deletion syndrome WP4806 WikiPathways EGFR tyrosine kinase inhibitor resistance WP710 WikiPathways DNA damage response (only ATM dependent) WP4241 WikiPathways Type 2 papillary renal cell carcinoma WP4018 WikiPathways Clear cell renal cell carcinoma pathways WP3614 WikiPathways Photodynamic therapy-induced HIF-1 survival signaling WP1539 WikiPathways Angiogenesis WP3672 WikiPathways lncRNA-mediated mechanisms of therapeutic resistance WP3657 WikiPathways Hematopoietic stem cell gene regulation by GABP alpha/beta complex WP4206 WikiPathways Hereditary leiomyomatosis and renal cell carcinoma pathway WP3646 WikiPathways Hepatitis C and hepatocellular carcinoma WP254 WikiPathways Apoptosis WP314 WikiPathways Fas ligand pathway and stress induction of heat shock proteins WP5182 WikiPathways Pro-survival signaling of neuroprotectin D1 WP384 WikiPathways Apoptosis modulation by HSP70 WP2507 WikiPathways Nanomaterial induced apoptosis WP5090 WikiPathways Complement system in neuronal development and plasticity WP3941 WikiPathways Oxidative damage response WP4864 WikiPathways Host-pathogen interaction of human coronaviruses - apoptosis WP3982 WikiPathways miRNA regulation of p53 pathway in prostate cancer WP4838 WikiPathways Regucalcin in proximal tubule epithelial kidney cells WP2371 WikiPathways Parkinsons disease pathway WP2036 WikiPathways TNF-related weak inducer of apoptosis (TWEAK) signaling pathway WP3959 WikiPathways DNA IR-double strand breaks and cellular response via ATM WP2059 WikiPathways Alzheimers disease and miRNA effects WP5124 WikiPathways Alzheimers disease WP4288 WikiPathways MTHFR deficiency WP2447 WikiPathways Amyotrophic lateral sclerosis (ALS) WP1433 WikiPathways Nucleotide-binding oligomerization domain (NOD) pathway WP4008 WikiPathways NO/cGMP/PKG mediated neuroprotection WP2328 WikiPathways Allograft rejection WP2513 WikiPathways Nanoparticle triggered regulated necrosis WP4396 WikiPathways Nonalcoholic fatty liver disease WP3617 WikiPathways Photodynamic therapy-induced NF-kB survival signaling WP5115 WikiPathways Network map of SARS-CoV-2 signaling pathway WP5180 WikiPathways DYRK1A WP4963 WikiPathways p53 transcriptional gene network WP1602 WikiPathways Nicotine effect on dopaminergic neurons WP536 WikiPathways Calcium regulation in cardiac cells WP3929 WikiPathways Chemokine signaling pathway WP2197 WikiPathways Endothelin pathways WP24 WikiPathways Peptide GPCRs WP455 WikiPathways GPCRs, class A rhodopsin-like WP4874 WikiPathways CAMKK2 pathway WP23 WikiPathways B cell receptor signaling pathway WP5205 WikiPathways Clock-controlled autophagy in bone metabolism WP2884 WikiPathways NRF2 pathway WP2272 WikiPathways Pathogenic Escherichia coli infection WP5039 WikiPathways SARS-CoV-2 innate immunity evasion and cell-specific immune response WP5117 WikiPathways Cohesin complex - Cornelia de Lange syndrome WP5118 WikiPathways SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome WP3644 WikiPathways NAD+ metabolism WP4240 WikiPathways Regulation of sister chromatid separation at the metaphase-anaphase transition WP3645 WikiPathways NAD+ biosynthetic pathways WP3995 WikiPathways Prion disease pathway WP3630 WikiPathways NAD metabolism, sirtuins and aging WP4210 WikiPathways Tryptophan catabolism leading to NAD+ production WP4191 WikiPathways Caloric restriction and aging WP500 WikiPathways Glycogen synthesis and degradation WP5173 WikiPathways Disorders of galactose metabolism WP534 WikiPathways Glycolysis and gluconeogenesis WP5220 WikiPathways Metabolic reprogramming in pancreatic cancer WP167 WikiPathways Eicosanoid synthesis WP5122 WikiPathways Prostaglandin and leukotriene metabolism in senescence WP5321 WikiPathways Prostaglandin and leukotriene metabolism in senescence WP5149 WikiPathways Lipid metabolism in senescent cells WP4719 WikiPathways Eicosanoid metabolism via cyclooxygenases (COX) WP5088 WikiPathways Prostaglandin signaling WP4586 WikiPathways Metabolism of alpha-linolenic acid WP98 WikiPathways Prostaglandin synthesis and regulation WP4891 WikiPathways COVID-19 adverse outcome pathway WP15 WikiPathways Selenium micronutrient network WP3287 WikiPathways Overview of nanoparticle effects WP4478 WikiPathways LTF danger signal response pathway WP5055 WikiPathways Burn wound healing WP5113 WikiPathways Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway WP5285 WikiPathways Immune infiltration in pancreatic cancer WP5137 WikiPathways Linoleic acid oxylipin metabolism WP3624 WikiPathways Lung fibrosis WP176 WikiPathways Folate metabolism WP5095 WikiPathways Overview of proinflammatory and profibrotic mediators WP4493 WikiPathways Cells and molecules involved in local acute inflammatory response WP4884 WikiPathways Pathogenesis of SARS-CoV-2 mediated by nsp9-nsp10 complex WP4925 WikiPathways Unfolded protein response WP5272 WikiPathways LDL- influence on CD14 and TLR4 WP530 WikiPathways Cytokines and inflammatory response WP3851 WikiPathways TLR4 signaling and tolerance WP4721 WikiPathways Eicosanoid metabolism via lipooxygenases (LOX) WP3893 WikiPathways Development and heterogeneity of the ILC family WP4481 WikiPathways Resistin as a regulator of inflammation WP4496 WikiPathways Signal transduction through IL1R WP4329 WikiPathways miRNA role in immune response in sepsis WP382 WikiPathways MAPK signaling pathway WP2203 WikiPathways Thymic stromal lymphopoietin (TSLP) signaling pathway WP1533 WikiPathways Vitamin B12 metabolism WP2849 WikiPathways Hematopoietic stem cell differentiation WP5222 WikiPathways 2q13 copy number variation syndrome WP4313 WikiPathways Ferroptosis WP4655 WikiPathways Cytosolic DNA-sensing pathway WP5083 WikiPathways Neuroinflammation and glutamatergic signaling WP5155 WikiPathways Arachidonic acid (AA, ARA) oxylipin metabolism WP4707 WikiPathways Aspirin and miRNAs WP4223 WikiPathways Ras signaling WP4756 WikiPathways Renin-angiotensin-aldosterone system (RAAS) WP2436 WikiPathways Dopamine metabolism WP3869 WikiPathways Cannabinoid receptor signaling WP3965 WikiPathways Lipid metabolism pathway WP4941 WikiPathways GPR143 in melanocytes and retinal pigment epithelium cells WP2636 WikiPathways Common pathways underlying drug addiction WP4249 WikiPathways Hedgehog signaling pathway WP35 WikiPathways G protein signaling pathways WP4540 WikiPathways Hippo signaling regulation pathways WP4321 WikiPathways Thermogenesis WP4541 WikiPathways Hippo-Merlin signaling dysregulation WP5283 WikiPathways Chronic hyperglycemia impairment of neuron function WP1403 WikiPathways AMP-activated protein kinase signaling WP3679 WikiPathways Cell-type dependent selectivity of CCK2R signaling WP247 WikiPathways Small ligand GPCRs WP1455 WikiPathways Serotonin transporter activity WP4220 WikiPathways Neurotransmitter disorders WP58 WikiPathways Monoamine GPCRs WP550 WikiPathways Biogenic amine synthesis WP465 WikiPathways Tryptophan metabolism WP727 WikiPathways Monoamine transport WP722 WikiPathways Serotonin HTR1 group and FOS pathway WP4156 WikiPathways Biosynthesis and regeneration of tetrahydrobiopterin and catabolism of phenylalanine WP3944 WikiPathways Serotonin and anxiety-related events WP3947 WikiPathways Serotonin and anxiety WP4698 WikiPathways Vitamin D-sensitive calcium signaling in depression WP2267 WikiPathways Synaptic vesicle pathway WP4900 WikiPathways Purinergic signaling WP117 WikiPathways GPCRs, other WP26 WikiPathways S1P receptor signal transduction WP3591 WikiPathways Sleep regulation WP4222 WikiPathways Phosphodiesterases in neuronal function WP4539 WikiPathways Synaptic signaling pathways associated with autism spectrum disorder WP51 WikiPathways Regulation of actin cytoskeleton WP3844 WikiPathways PI3K-AKT-mTOR signaling pathway and therapeutic opportunities WP4582 WikiPathways Cancer immunotherapy by CTLA4 blockade WP4217 WikiPathways Ebola virus infection in host WP3915 WikiPathways Angiopoietin-like protein 8 regulatory pathway WP4239 WikiPathways Epithelial to mesenchymal transition in colorectal cancer WP3937 WikiPathways Microglia pathogen phagocytosis pathway WP4566 WikiPathways Translation inhibitors in chronically activated PDGFRA cells WP4787 WikiPathways Osteoblast differentiation and related diseases WP395 WikiPathways IL-4 signaling pathway WP4829 WikiPathways mBDNF and proBDNF regulation of GABA neurotransmission WP4871 WikiPathways Kisspeptin/kisspeptin receptor system in the ovary WP5191 WikiPathways Resolvin E1 and resolvin D1 signaling pathways promoting inflammation resolution WP244 WikiPathways Alpha 6 beta 4 signaling pathway WP524 WikiPathways G13 signaling pathway WP585 WikiPathways Interferon type I signaling pathways WP3935 WikiPathways Leptin-insulin signaling overlap WP5181 WikiPathways Roles of ceramides in development of insulin resistance WP205 WikiPathways IL-7 signaling pathway WP2643 WikiPathways Nanoparticle-mediated activation of receptor signaling WP2533 WikiPathways Glycerophospholipid biosynthetic pathway WP364 WikiPathways IL6 signaling pathway WP2332 WikiPathways Interleukin-11 signaling pathway WP4971 WikiPathways Phosphoinositides metabolism WP195 WikiPathways IL-1 signaling pathway WP5072 WikiPathways Modulators of TCR signaling and T cell activation WP5192 WikiPathways Modulation of PI3K-Akt-mTOR signaling by bioactive sphingolipids WP4549 WikiPathways Fragile X syndrome WP22 WikiPathways IL-9 signaling pathway WP5101 WikiPathways Congenital generalized lipodystrophy WP4141 WikiPathways PI3K/AKT/mTOR - vitamin D3 signaling WP1584 WikiPathways Type II diabetes mellitus WP5074 WikiPathways Kallmann syndrome WP581 WikiPathways EPO receptor signaling WP5200 WikiPathways Dravet syndrome WP2112 WikiPathways IL-17 signaling pathway WP3676 WikiPathways BDNF-TrkB signaling WP3850 WikiPathways Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling WP4558 WikiPathways Overview of interferons-mediated signaling pathway WP4136 WikiPathways Fibrin complement receptor 3 signaling pathway WP2038 WikiPathways Microtubule cytoskeleton regulation WP5144 WikiPathways NRP1-triggered signaling pathways in pancreatic cancer WP4906 WikiPathways 3q29 copy number variation syndrome WP1982 WikiPathways Sterol regulatory element-binding proteins (SREBP) signaling WP2249 WikiPathways Metastatic brain tumor WP3872 WikiPathways Regulation of apoptosis by parathyroid hormone-related protein WP1471 WikiPathways Target of rapamycin signaling WP5323 WikiPathways Fatty Acids and Lipoproteins Transport in Hepatocytes WP4301 WikiPathways Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells WP3298 WikiPathways Melatonin metabolism and effects WP5236 WikiPathways Markers of kidney cell lineage WP3678 WikiPathways Amplification and expansion of oncogenic pathways as metastatic traits WP4317 WikiPathways Mitochondrial fatty acid synthesis pathway WP5031 WikiPathways Biotin metabolism, including IMDs WP3925 WikiPathways Amino acid metabolism WP4595 WikiPathways Urea cycle and associated pathways WP106 WikiPathways Alanine and aspartate metabolism WP5312 WikiPathways Metabolic pathways of fibroblasts WP4290 WikiPathways Metabolic reprogramming in colon cancer WP4157 WikiPathways GABA metabolism (aka GHB) WP4583 WikiPathways Biomarkers for urea cycle disorders WP2453 WikiPathways TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc) WP497 WikiPathways Urea cycle and metabolism of amino groups WP2911 WikiPathways miRNA targets in ECM and membrane receptors WP4966 WikiPathways Fluoroacetic acid toxicity WP2855 WikiPathways Dopaminergic neurogenesis WP453 WikiPathways Inflammatory response pathway WP5036 WikiPathways Angiotensin II receptor type 1 pathway WP2035 WikiPathways Follicle stimulating hormone (FSH) signaling pathway WP4553 WikiPathways FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma WP4153 WikiPathways Degradation pathway of sphingolipids, including diseases WP4584 WikiPathways Biomarkers for pyrimidine metabolism disorders WP4225 WikiPathways Pyrimidine metabolism and related diseases WP4022 WikiPathways Pyrimidine metabolism WP1601 WikiPathways Fluoropyrimidine activity WP4589 WikiPathways Major receptors targeted by epinephrine and norepinephrine WP4760 WikiPathways PKC-gamma calcium signaling pathway in ataxia WP4923 WikiPathways Autophagy WP4905 WikiPathways 1q21.1 copy number variation syndrome WP4577 WikiPathways Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway WP3934 WikiPathways Leptin and adiponectin WP3878 WikiPathways ATM signaling in development and disease WP3595 WikiPathways mir-124 predicted interactions with cell cycle and differentiation WP2011 WikiPathways SREBF and miR33 in cholesterol and lipid homeostasis WP3879 WikiPathways 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression WP1981 WikiPathways Thyroxine (thyroid hormone) production WP363 WikiPathways Wnt signaling pathway WP5329 WikiPathways Cholesterol biosynthesis pathway in hepatocytes WP4538 WikiPathways Regulatory circuits of the STAT3 signaling pathway WP422 WikiPathways MAPK cascade WP2637 WikiPathways Interleukin-1 (IL-1) structural pathway WP734 WikiPathways Serotonin receptor 4/6/7 and NR3C signaling WP732 WikiPathways Serotonin receptor 2 and ELK-SRF/GATA4 signaling WP4767 WikiPathways FGFR3 signaling in chondrocyte proliferation and terminal differentiation WP4535 WikiPathways Envelope proteins and their potential roles in EDMD physiopathology WP2868 WikiPathways TCA cycle nutrient use and invasiveness of ovarian cancer WP4269 WikiPathways Ethanol metabolism production of ROS by CYP2E1 WP2815 WikiPathways Mammary gland development pathway - Involution (Stage 4 of 4) WP1434 WikiPathways Osteopontin signaling WP3301 WikiPathways MFAP5-mediated ovarian cancer cell motility and invasiveness WP4560 WikiPathways MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement WP4585 WikiPathways Cancer immunotherapy by PD-1 blockade WP5231 WikiPathways Hippocampal synaptogenesis and neurogenesis WP2516 WikiPathways ATM signaling pathway WP5221 WikiPathways 2q11.2 copy number variation syndrome WP5198 WikiPathways Inflammatory bowel disease signaling WP4389 WikiPathways Bile acids synthesis and enterohepatic circulation WP3859 WikiPathways TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition WP3668 WikiPathways Hypothesized pathways in pathogenesis of cardiovascular disease WP4875 WikiPathways Disruption of postsynaptic signaling by CNV WP4331 WikiPathways Neovascularisation processes WP400 WikiPathways p38 MAPK signaling pathway WP4534 WikiPathways Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms WP3302 WikiPathways eIF5A regulation in response to inhibition of the nuclear export system WP2864 WikiPathways Apoptosis-related network due to altered Notch3 in ovarian cancer WP5277 WikiPathways Steroid hormone precursor biosynthesis WP5279 WikiPathways Mineralocorticoid biosynthesis WP5280 WikiPathways Glucocorticoid biosynthesis WP4524 WikiPathways Alternative pathway of fetal androgen synthesis WP4523 WikiPathways Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism WP696 WikiPathways Benzo(a)pyrene metabolism WP702 WikiPathways Metapathway biotransformation Phase I and II WP496 WikiPathways Steroid biosynthesis WP554 WikiPathways ACE inhibitor pathway WP4969 WikiPathways RAS and bradykinin pathways in COVID-19 WP4016 WikiPathways DNA IR-damage and cellular response via ATR WP1742 WikiPathways TP53 network WP186 WikiPathways Homologous recombination WP1545 WikiPathways miRNAs involved in DNA damage response WP4946 WikiPathways DNA repair pathways, full network WP3613 WikiPathways Photodynamic therapy-induced unfolded protein response WP4861 WikiPathways Endoplasmic reticulum stress response in coronavirus infection WP3853 WikiPathways ERK pathway in Huntingtons disease WP2509 WikiPathways Nanoparticle triggered autophagic cell death WP4932 WikiPathways 7q11.23 copy number variation syndrome WP4562 WikiPathways Canonical NF-kB pathway WP4961 WikiPathways STING pathway in Kawasaki-like disease and COVID-19 WP4479 WikiPathways Supression of HMGB1 mediated inflammation by THBD WP4480 WikiPathways Altered glycosylation of MUC1 in tumor microenvironment WP3865 WikiPathways Novel intracellular components of RIG-I-like receptor pathway WP4482 WikiPathways Vitamin D in inflammatory diseases WP262 WikiPathways Ebstein-Barr virus LMP1 signaling WP3858 WikiPathways Toll-like receptor signaling related to MyD88 WP3849 WikiPathways MAPK and NFkB signaling pathways inhibited by Yersinia YopJ WP288 WikiPathways Nod-like receptor (NLR) signaling pathway WP4876 WikiPathways Activation of NLRP3 inflammasome by SARS-CoV-2 WP4788 WikiPathways Autosomal recessive osteopetrosis pathways WP4337 WikiPathways ncRNAs involved in STAT3 signaling in hepatocellular carcinoma WP2583 WikiPathways T cell receptor and co-stimulatory signaling WP3890 WikiPathways Nanomaterial-induced inflammasome activation WP2865 WikiPathways IL1 and megakaryocytes in obesity WP5183 WikiPathways SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction WP3926 WikiPathways ApoE and miR-146 in inflammation and atherosclerosis WP3656 WikiPathways Interleukin-1 induced activation of NF-kB WP3877 WikiPathways MYD88 distinct input-output pathway WP5174 WikiPathways Ulcerative colitis signaling WP4559 WikiPathways Interactions between immune cells and microRNAs in tumor microenvironment WP5038 WikiPathways Mitochondrial immune response to SARS-CoV-2 WP5121 WikiPathways Sphingolipid metabolism in senescence WP2877 WikiPathways Vitamin D receptor pathway WP3969 WikiPathways H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity WP4970 WikiPathways Galanin receptor pathway WP2878 WikiPathways PPAR-alpha pathway WP2572 WikiPathways Primary focal segmental glomerulosclerosis (FSGS) WP4790 WikiPathways FGF23 signaling in hypophosphatemic rickets and related disorders WP4844 WikiPathways Influence of laminopathies on Wnt signaling WP4258 WikiPathways lncRNA in canonical Wnt signaling and colorectal cancer WP531 WikiPathways DNA mismatch repair WP5114 WikiPathways Nucleotide excision repair in xeroderma pigmentosum WP4753 WikiPathways Nucleotide excision repair WP466 WikiPathways DNA replication WP4752 WikiPathways Base excision repair WP5292 WikiPathways Glycosphingolipid metabolism WP5275 WikiPathways Ether lipid biosynthesis WP1422 WikiPathways Sphingolipid pathway WP4352 WikiPathways Ciliary landscape WP5120 WikiPathways Inclusion body myositis WP2485 WikiPathways NAD biosynthesis II (from tryptophan) WP528 WikiPathways Acetylcholine synthesis WP3933 WikiPathways Kennedy pathway from sphingolipids WP197 WikiPathways Cholesterol biosynthesis pathway WP5193 WikiPathways Cholesterol synthesis disorders WP5333 WikiPathways Cholesterol metabolism WP4718 WikiPathways Cholesterol metabolism with Bloch and Kandutsch-Russell pathways WP5304 WikiPathways Cholesterol metabolism WP1992 WikiPathways Genes targeted by miRNAs in adipocytes WP698 WikiPathways Glucuronidation WP1604 WikiPathways Codeine and morphine metabolism WP697 WikiPathways Estrogen metabolism WP691 WikiPathways Tamoxifen metabolism WP5276 WikiPathways Estrogen metabolism WP229 WikiPathways Irinotecan pathway WP3874 WikiPathways Canonical and non-canonical TGF-B signaling WP3670 WikiPathways Interactions between LOXL4 and oxidative stress pathway WP2406 WikiPathways Cardiac progenitor differentiation WP2289 WikiPathways Drug induction of bile acid pathway WP299 WikiPathways Nuclear receptors in lipid metabolism and toxicity WP43 WikiPathways Oxidation by cytochrome P450 WP2879 WikiPathways Farnesoid X receptor pathway WP4174 WikiPathways Metabolism of tetrahydrocannabinol (THC) WP4917 WikiPathways Proximal tubule transport WP678 WikiPathways Arachidonate epoxygenase / epoxide hydrolase WP206 WikiPathways Fatty acid omega-oxidation WP5238 WikiPathways Cholestasis WP3640 WikiPathways Imatinib and chronic myeloid leukemia WP5176 WikiPathways Disorders of bile acid synthesis and biliary transport WP5190 WikiPathways Creatine pathway WP3300 WikiPathways Dual hijack model of Vif in HIV infection WP4860 WikiPathways Hijack of ubiquitination by SARS-CoV-2 WP383 WikiPathways Striated muscle contraction pathway WP5314 WikiPathways Lactate shuttle in glial cells WP5171 WikiPathways Leukotriene metabolic pathway WP100 WikiPathways Glutathione metabolism WP2525 WikiPathways Trans-sulfuration, one-carbon metabolism and related pathways WP690 WikiPathways Polyol pathway WP1946 WikiPathways Cori cycle WP5178 WikiPathways Disorders of fructose metabolism WP5133 WikiPathways Non-classical role of vitamin D WP4883 WikiPathways SARS-CoV-2 and ACE2 receptor: molecular mechanisms WP4799 WikiPathways Downregulation of ACE2 by SARS-CoV-2 spike protein WP5076 WikiPathways Soluble ACE2-mediated cell entry of SARS-CoV-2 WP4818 WikiPathways Conversion of angiotensinogen to angiotensin II WP5089 WikiPathways Kinin-Kallikrein pathway WP477 WikiPathways Cytoplasmic ribosomal proteins WP129 WikiPathways Matrix metalloproteinases WP5315 WikiPathways Sebaleic acid formation and metabolism WP558 WikiPathways Complement and coagulation cascades WP272 WikiPathways Blood clotting cascade WP4927 WikiPathways COVID-19, thrombosis and anticoagulation WP2806 WikiPathways Complement system WP5186 WikiPathways Vitamin K metabolism and activation of dependent proteins WP699 WikiPathways Aflatoxin B1 metabolism WP2646 WikiPathways Lidocaine metabolism WP2816 WikiPathways Felbamate metabolism WP3891 WikiPathways Benzene metabolism WP5066 WikiPathways FOXA2 pathway WP4462 WikiPathways Platelet-mediated interactions with vascular and circulating cells WP5218 WikiPathways Extrafollicular and follicular B cell activation by SARS-CoV-2 WP5044 WikiPathways Kynurenine pathway and links to cell senescence WP3633 WikiPathways Caffeine and theobromine metabolism WP2542 WikiPathways Sulindac metabolic pathway WP3871 WikiPathways Valproic acid pathway WP5188 WikiPathways Retinol metabolism WP5029 WikiPathways Amino acid transport defects (IEMs) WP5284 WikiPathways Cell interactions of the pancreatic cancer microenvironment WP5092 WikiPathways Interactions of natural killer cells in pancreatic cancer WP3958 WikiPathways GPR40 pathway WP2118 WikiPathways Arrhythmogenic right ventricular cardiomyopathy WP4726 WikiPathways Sphingolipid metabolism: integrated pathway WP4962 WikiPathways Airway smooth muscle cell contraction WP5294 WikiPathways Sildenafil treatment WP2874 WikiPathways Liver X receptor pathway WP1600 WikiPathways Nicotine metabolism in liver cells WP694 WikiPathways Arylamine metabolism WP3942 WikiPathways PPAR signaling pathway WP623 WikiPathways Oxidative phosphorylation WP111 WikiPathways Electron transport chain: OXPHOS system in mitochondria WP4324 WikiPathways Mitochondrial complex I assembly model OXPHOS system WP78 WikiPathways TCA cycle (aka Krebs or citric acid cycle) WP4920 WikiPathways Mitochondrial complex II assembly WP4236 WikiPathways Krebs cycle disorders WP3599 WikiPathways Transcription factor regulation in adipogenesis WP2895 WikiPathways Differentiation of white and brown adipocyte WP5265 WikiPathways Neurogenesis regulation in the olfactory epithelium WP3 WikiPathways Transcriptional activation by NRF2 in response to phytochemicals WP4357 WikiPathways NRF2-ARE regulation WP4518 WikiPathways Gamma-glutamyl cycle for the biosynthesis and degradation of glutathione, including diseases WP3953 WikiPathways mRNA, protein, and metabolite inducation pathway by cyclosporin A WP4504 WikiPathways Cysteine and methionine catabolism WP5050 WikiPathways TCA cycle in senescence WP5166 WikiPathways Glyoxylate metabolism WP4292 WikiPathways Methionine metabolism leading to sulfur amino acids and related disorders WP2333 WikiPathways Trans-sulfuration pathway WP241 WikiPathways One-carbon metabolism WP1589 WikiPathways Folate-alcohol and cancer pathway hypotheses WP3580 WikiPathways Methionine de novo and salvage pathway WP4259 WikiPathways Disorders of folate metabolism and transport WP1495 WikiPathways Glycine metabolism WP4688 WikiPathways Serine metabolism WP4271 WikiPathways Vitamin B12 disorders WP4159 WikiPathways GABA receptor signaling WP4148 WikiPathways Splicing factor NOVA regulated synaptic proteins WP501 WikiPathways GPCRs, class C metabotropic glutamate, pheromone WP4629 WikiPathways Aerobic glycolysis WP2456 WikiPathways HIF1A and PPARG regulation of glycolysis WP4494 WikiPathways Selective expression of chemokine receptors during T-cell polarization WP619 WikiPathways Type II interferon signaling WP4484 WikiPathways Control of immune tolerance by vasoactive intestinal peptide WP4495 WikiPathways IL-10 anti-inflammatory signaling pathway WP4950 WikiPathways 16p11.2 distal deletion syndrome WP4720 WikiPathways Eicosanoid metabolism via cytochrome P450 monooxygenases pathway WP411 WikiPathways mRNA processing WP4336 WikiPathways ncRNAs involved in Wnt signaling in hepatocellular carcinoma WP428 WikiPathways Wnt signaling WP357 WikiPathways Fatty acid biosynthesis WP4724 WikiPathways Omega-9 fatty acid synthesis WP4723 WikiPathways Omega-3 / omega-6 fatty acid synthesis WP368 WikiPathways Mitochondrial long chain fatty acid beta-oxidation WP5061 WikiPathways Fatty acid transporters WP143 WikiPathways Fatty acid beta-oxidation WP5064 WikiPathways 7-oxo-C and 7-beta-HC pathways WP4224 WikiPathways Purine metabolism and related disorders WP3634 WikiPathways Insulin signaling in adipocytes (normal condition) WP3635 WikiPathways Insulin signaling in adipocytes (diabetic condition) WP430 WikiPathways Statin inhibition of cholesterol production WP5318 WikiPathways Female steroid hormones in cardiomyocyte energy metabolism WP1531 WikiPathways Vitamin D metabolism WP325 WikiPathways Triacylglyceride synthesis WP716 WikiPathways Vitamin A and carotenoid metabolism WP4722 WikiPathways Glycerolipids and glycerophospholipids WP4792 WikiPathways Purine metabolism WP2359 WikiPathways Parkin-ubiquitin proteasomal system pathway WP4686 WikiPathways Leucine, isoleucine and valine metabolism WP410 WikiPathways Exercise-induced circadian regulation WP4921 WikiPathways Mitochondrial complex III assembly WP516 WikiPathways Hypertrophy model WP3927 WikiPathways BMP signaling in eyelid development WP4150 WikiPathways Wnt signaling in kidney disease WP5211 WikiPathways Glucose metabolism in triple-negative breast cancer cells WP4186 WikiPathways Somatroph axis (GH) and its relationship to dietary restriction and aging WP4542 WikiPathways Leukocyte-intrinsic Hippo pathway functions WP3658 WikiPathways Wnt/beta-catenin signaling pathway in leukemia WP5102 WikiPathways Familial partial lipodystrophy WP4149 WikiPathways White fat cell differentiation WP107 WikiPathways Translation factors WP4823 WikiPathways Genes controlling nephrogenesis WP2805 WikiPathways exRNA mechanism of action and biogenesis WP5053 WikiPathways Development of ureteric collection system